Leo’s Vasodilation Research Blend

Leo’s Vasodilation Research Blend is a comprehensive amino acid formulation designed for preclinical investigation of nitric oxide biosynthesis, vascular tone regulation, and endothelial function. Supplied in a 20mL vial, this multi-substrate blend delivers a full spectrum of urea cycle and nitrogen metabolism intermediates alongside branched-chain amino acids and osmoprotective agents at research-validated concentrations.

Vial & Dosing Specifications

Total Volume	20 mL per vial
Reference Dose Unit	Per 1 mL
Storage Form	Aqueous solution
Storage Information	Store in a refrigerated environment free of exposure to sunlight, moisture, or excessive heat.
Grade	Research Grade — For Research Use Only
Purity	All components ≥98% (HPLC verified)

Composition Per 1 mL

Component	Concentration (per mL)
L-Arginine	100 mg/mL
L-Citrulline	100 mg/mL
L-Ornithine	100 mg/mL
L-Glutamine	100 mg/mL
L-Glycine	100 mg/mL
L-Lysine	50 mg/mL
BCAA 2:1:1 (Leucine:Isoleucine:Valine)	50 mg/mL
Taurine	50 mg/mL

Component Research Overview

L-Arginine (100 mg/mL): The primary substrate for nitric oxide synthase (NOS)-mediated NO production; central to endothelial vasodilation research, vascular biology, and immunomodulatory pathway studies.

L-Citrulline (100 mg/mL): A key urea cycle intermediate that recycles to L-arginine, sustaining NO biosynthesis. Studied for its role in maintaining intracellular arginine availability and attenuating NOS substrate depletion in vascular models.

L-Ornithine (100 mg/mL): A urea cycle intermediate and precursor to polyamines; investigated for its roles in ammonia detoxification, cellular proliferation support, and growth hormone secretagogue activity in research frameworks.

L-Glutamine (100 mg/mL): The most abundant amino acid in circulation; essential for nitrogen transport, intestinal barrier integrity research, immune cell fuel utilization studies, and glutathione precursor biosynthesis.

L-Glycine (100 mg/mL): The simplest amino acid with roles in collagen synthesis, inhibitory neurotransmission (glycine receptor agonism), anti-inflammatory signaling, and mitochondrial one-carbon metabolism research.

L-Lysine (50 mg/mL): An essential amino acid studied for its role in collagen cross-linking, carnitine biosynthesis support, antiviral research (notably HSV models), and calcium absorption pathway investigation.

BCAA 2:1:1 — Leucine:Isoleucine:Valine (50 mg/mL): Branched-chain amino acids in the classic 2:1:1 ratio; investigated for mTORC1-mediated protein synthesis signaling, muscle protein catabolism inhibition, and metabolic substrate research in exercise physiology models.

Taurine (50 mg/mL): A sulfonic amino acid with antioxidant, osmoregulatory, and membrane-stabilizing properties; studied in cardiovascular, retinal, and neurological research for its role in calcium modulation and mitochondrial protection.

Research Applications

Leo’s Vasodilation Research Blend is designed for endothelial NO signaling studies, vascular smooth muscle relaxation assays, urea cycle pathway research, amino acid transport and utilization models, and cardiovascular physiology investigation. The coordinated inclusion of both proximal and downstream NO pathway substrates alongside structural and osmoprotective amino acids supports comprehensive multi-parameter vascular biology research protocols.

Quality Assurance & Supplier Commitment

We maintain longstanding relationships with leading peptide lyophilizers and raw material suppliers, selected through an exhaustive vetting process that evaluates manufacturing practices, analytical capabilities, and regulatory compliance. Our API sourcing protocol includes certificate of analysis review, third-party analytical testing, and periodic supplier audits to ensure consistent purity, potency, and sterility standards across all product lines.

Each batch undergoes meticulous quality control verification prior to release, including HPLC purity analysis, mass spectrometry confirmation, and endotoxin testing where applicable. Our commitment to sourcing integrity ensures researchers receive material of the highest available quality.

RESEARCH USE ONLY DISCLAIMER

This product is intended exclusively for in vitro research and laboratory use by qualified professionals. It is not approved for human or veterinary use, consumption, or therapeutic application. This product has not been evaluated by the FDA or any equivalent regulatory authority. The seller makes no claims regarding its safety, efficacy, or suitability for any medical, diagnostic, or therapeutic purpose. All research must comply with applicable local, state, and federal regulations.